L Ergothioneine Powder

Ergothioneine (Ergo) is a naturally occurring amino acid and a derivative of histidine with thiol/thione properties. L ergothioneine powder is primarily found in mushrooms and bacteria, with lower levels present in foods like king crab, beef, pork, lamb, and chicken. Although L ergothioneine powder is present in the foods we consume, its biosynthesis has only been observed in certain bacteria and fungi. In humans, Ergo is transported by a specific protein called OCTN1, which enhances its bioavailability and retention. This unique transport mechanism has sparked speculation about the potential importance of Ergo to human health, as specific transporters for non-nutrient bioactive compounds are uncommon.

Ergothioneine (Ergo) shares some similarities with vitamins in terms of its essential nature and potential role in promoting health. While Ergo is not officially classified as a vitamin, it has been proposed by scientist Bruce Ames as one of the compounds that can be considered a "longevity vitamin."

Like vitamins, Ergo is not synthesized in the body and must be obtained from external sources, primarily through dietary intake. It is present in certain foods, with mushrooms and bacteria being particularly rich sources. However, Ergo's biosynthesis has only been observed in specific bacteria and fungi, not in humans.

The concept of "longevity vitamins" introduced by Ames suggests that certain compounds, including Ergo, play a crucial role in supporting the function of longevity proteins. These proteins are involved in various biological processes that impact aging and disease risk. In the context of the triage theory proposed by Ames, deficiencies in these longevity vitamins may lead to short-term survival prioritization at the expense of long-term health.

While Ergo may not fit into the traditional definition of vitamins, its inclusion in the concept of longevity vitamins highlights its potential significance for overall health and well-being. However, it's important to note that further research is needed to fully understand the extent of Ergo's role and its specific mechanisms of action in promoting healthy aging.

The Triage Theory, proposed by renowned scientist Bruce Ames, PhD, suggests that when the body lacks a certain vitamin or mineral, it must make a decision on how to allocate its limited supply. Should it be used for immediate needs or to support overall well-being? A recent study by Ames indicated that the body prioritizes the use of scarce micronutrients for short-term survival, potentially compromising long-term health. However, Ames proposed that if the body is consistently well-supplied with essential nutrients, it would not need to make such choices, promoting healthy aging.

In 2018, Ames introduced the concept of "longevity vitamins" alongside the existing classifications of vitamins and minerals. Longevity vitamins are compounds necessary for the function of longevity proteins, and deficiencies in these vitamins may accelerate the risk of age-related diseases. Ergo falls into this category of longevity vitamins, as it is not synthesized in the body and the triage hypothesis is applicable to it—deficiencies in these compounds may lead to short-term maintenance at the expense of long-term health.

Unfortunately, nutrient deficiencies are prevalent in the United States and other regions. Initial evidence suggests that Ergo levels in the American food supply may be compromised due to reduced fungal populations in agricultural soils caused by certain cultivation practices. Ames postulated that appropriate supplementation or an improved diet including longevity vitamins like L ergothioneine powder could potentially reduce the associated risks of chronic diseases and premature aging.

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