Neu5ac and Neu5gc
Synonyms: Sialic acid (SA)
Product Number: 30404
CAS Number: 131-48-6
Molecular Formula: C11H19NO9
Description
Neu5Ac and Neu5Gc (N-acetylneuraminic acid and N-glycolylneuraminic acid) are two different types of sialic acids, which are a family of nine-carbon acidic sugars that are typically found on the outer surface of many cell types in mammals.
The main difference between Neu5Ac and Neu5Gc is that Neu5Ac has an N-acetyl group (-COCH3) at the carbon-5 position, while Neu5Gc has a N-glycolyl group (-COCH2OH) at the same position.
Although both Neu5Ac and Neu5Gc are found in some animal tissues, Neu5Gc is absent in humans due to a mutation that occurred in a common ancestor of humans and chimpanzees. This means that while Neu5Ac is the predominant form of sialic acid in humans, Neu5Gc is found in many other mammals, such as cows and pigs.
The difference between Neu5Ac and Neu5Gc has been of interest to researchers because Neu5Gc can be immunogenic in humans, meaning that it can trigger an immune response when consumed or incorporated into human tissues. This may have implications for the development of certain diseases, such as cancer and inflammation, and may also have implications for xenotransplantation (the use of animal organs in humans).
N-acetylneuraminic acid, also known as sialic acid, is a type of sugar molecule that is found in many tissues and fluids of the human body. It is involved in various biological processes and has several functions that are important for human health.
Supports immune function: N-acetylneuraminic acid is present on the surface of many cells in the immune system, including white blood cells. It plays a role in regulating immune cell signaling and activation, which is important for fighting infections and preventing autoimmune diseases.
Facilitates communication between cells: N-acetylneuraminic acid is also present on the surface of many other types of cells in the body. It acts as a signaling molecule that helps cells communicate with each other and with the extracellular environment. This is important for processes such as cell growth, differentiation, and migration.
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Product Name: |
acetylneuraminic acid |
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Synonyms |
Sialic acid (SA) |
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Product Number: |
30404 |
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CAS Number: |
131-48-6 |
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Molecular Formula: |
C11H19NO9 |
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Molecular Weight: |
309.27 |
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Form: |
Powder |
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Source: |
Fermentation (from corn) |
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Storage Conditions: |
Preserve in airtight containers, protected from light and store at cool and dry place. |
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Description: |
N-acetylneuraminic acid, also known as Sialic acid (SA), it is a general term for a class of acidic amino sugars with 9 carbon atoms and structure of pyranose, which are widely distributed in nature |
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Mechanism of Action: |
Sialic Acid plays a significant role in HMOs (Human Milk Oligosaccharides), which it can practically promote infant formulas more close to the breast milk. Also, Sialic acid is an important building block for brain gangliosides, which are complex molecules displayed on the surface of neurons with a key role in brain development. And it can functionally repair the damaged neural cells, epithelial cells and immune cells and enhance its capability against virus and bacteria. Moreover, two pivotal functions of Sialic acid in cosmetic are anti-aging and nourishing whitening. |
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Heavy Metals Limit: |
Pb ≤ 0.5ppm Cd ≤ 0.5ppm As ≤ 0.4ppm Hg ≤ 0.2ppm |
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